منابع مشابه
Interference in a radioimmunoassay for human thyrotropin.
Abnormally high plasma thyrotropin values were found by radioimmunoassay in some patients when an antiserum to porcine thyrotropin was used, normal results being obtained with an antiserum raised to human thyrotropin. These discrepancies were found in some subjects with no biochemical or clinical evidence of hypothyroidism and occasionally in sera from patients with unequivocal hyperthyroidism....
متن کاملRadioimmunoassay of Human Plasma Thyrotropin.
Many pituitary hormones possess partial or complete immunological species specificity. Earlier reports suggested that thyrotropin (TSH) did not have such specificity since the biological activity of human pituitary or plasma TSH could be neutralized by antisera to bovine TSH in doses similar to that which blocked the biological activity of bovine TSH (2, 3). However, recent studies have shown t...
متن کاملDevelopment and validation of a radioimmunoassay for thyrotropin in cattle.
In mammals, thyrotropin, or thyroid-stimulating hormone (TSH), assay is used for the diagnosis of primary hypothyroidism. Hypothyroidism is the most common type of thyroid disorder in cattle. The aim of this study was to develop and validate, under physiologic and pathologic conditions, a radioimmunoassay (RIA) for bovine TSH (bTSH). Double RIA was performed with purified bTSH and specific bovi...
متن کاملA thyrotropin radioimmunoassay kit evaluated vs two reference assays.
We evaluated a double-antibody radioimmunoassay kit for thyrotropin that includes calibrators prepared in a matrix of human serum and involves overnight nonequilibrium. Results were compared with those from two reference assays for thyrotropin. The range of within-assay CVs for the kit for thyrotropin values between 0.9 and 2.4 milli-int. units/L was 2.2 to 5.3%, that for between-assay CVs was ...
متن کاملSimultaneous radioimmunoassay of thyrotropin and thyroxine in human serum.
The importance of early diagnois and treatment of congenital hypothyroidism has been well established, and several screening programs have been undertaken to detect neonates with this disorder by measurement of concentrations of thyrotropin or thyroxine in the serum. However, measurement of either hormone alone may fail to identify all affected patients. Accordingly, we have established a simul...
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ژورنال
عنوان ژورنال: Nihon Chikusan Gakkaiho
سال: 1979
ISSN: 1346-907X,1880-8255
DOI: 10.2508/chikusan.50.803